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Pharmacokinetics of mycophenolic acid and its effect on CD4+ and CD8+ T cells after oral administration of mycophenolate mofetil to healthy cats

机译：霉酚酸酯对健康猫的口服给药后霉酚酸的药代动力学及其对CD4 +和CD8 + T细胞的影响

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摘要

BackgroundMycophenolate mofetil (MMF) is an immunosuppressant used in human and veterinary medicine. Little pharmacokinetic and pharmacodynamic information on MMF is available in cats.

机译：背景霉酚酸酯（MMF）是一种用于人类和兽医学的免疫抑制剂。在猫中几乎没有关于MMF的药代动力学和药效学信息。

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期刊名称 Journal of Veterinary Internal Medicine
作者
Jennifer E. Slovak; Julianne K. Hwang; Sol M. Rivera; Nicolas F. Villarino;
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作者单位

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年(卷),期 2019(33),5
年度 2019
页码 2020–2028
总页数 9
原文格式 PDF
正文语种
中图分类动物医学（兽医学）;
关键词
cats immunosuppressant mycophenolate mofetil pharmacodynamics pharmacokinetics;

机译：猫;免疫抑制剂;霉酚酸酯;药效学;药代动力学;

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专利

1. Pharmacokinetics of mycophenolic acid and its effect on CD4+ and CD8+ T cells after oral administration of mycophenolate mofetil to healthy cats [J] . Jennifer E. Slovak, Julianne K. Hwang, Sol M. Rivera, Journal of Veterinary Internal Medicine . 2019,第5期

机译：霉酚酸酯对健康猫的口服给药后，霉酚酸的药代动力学及其对CD4 +和CD8 + T细胞的影响
2. Pharmacokinetics of Mycophenolic Acid after Intravenous Administration of Mycophenolate Mofetil to Healthy Cats [J] . Pedro Carlos da Rocha-Neto, Carlos Roberto Batista de Morais, Euler Maciel Dantas, Journal of Veterinary Internal Medicine . 2017,第6期

机译：霉酚酸酯对健康猫静脉给药后的霉酚酸药代动力学
3. Pharmacokinetics and Bioavailability of Mycophenolic Acid After Intravenous Administration and Oral Administration of Mycophenolate Mofetil to Heart Transplant Recipients. [J] . Armstrong VW, Shipkova M, Koerfer R, Therapeutic Drug Monitoring . 2005,第3期

机译：静脉给予麦考酚酸酯后，麦考酚酸酯对心脏移植受者的药代动力学和生物利用度。
4. Overcoming Challenges in Developing a Rugged LC-MS/MS Method for Mycophenolate Mofetil and Mycophenolic Acid in Human Plasma [C] . Nick Peng, Iffat Balkhi, Anita Towers, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：在人血浆中克服霉菌MoFetil和霉酚酸的粗糙LC-MS / MS方法克服挑战
5. Novel in vitro cell culture models for studying pharmacokinetic drug-drug interactions following oral administration [D] . Kwatra, Deep 2011

机译：用于研究口服给药后药代动力学药物相互作用的新型体外细胞培养模型
6. Pharmacokinetics of Mycophenolic Acid after Intravenous Administration of Mycophenolate Mofetil to Healthy Cats [O] . J.E. Slovak, S.M. Rivera, J.K. Hwang, 2017

机译：霉酚酸酯对健康猫静脉给药后的霉酚酸药代动力学
7. Pharmacokinetics of Mycophenolic Acid after Intravenous Administration of Mycophenolate Mofetil to Healthy Cats [O] . J.E. Slovak, S.M. Rivera, J.K. Hwang, 2017

机译：静脉内施用霉酚酸盐酸盐菌霉菌酸盐酸盐至健康猫的药代动力学

Pharmacokinetics of mycophenolic acid and its effect on CD4+ and CD8+ T cells after oral administration of mycophenolate mofetil to healthy cats

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