首页> 外国专利> Pharmaceutical formulation in the form of dry granulation product containing mycophenolate mofetil or mycophenolic acid and process for preparing thereof

Pharmaceutical formulation in the form of dry granulation product containing mycophenolate mofetil or mycophenolic acid and process for preparing thereof

机译:含有麦考酚酸酯或麦考酚酸的干法制粒产品形式的药物制剂及其制备方法

摘要

In the present invention, there is disclosed a high dose, dry granulation and aqueous oral suspension of mycophenolate mofetil or mycophenolic acid, containing 7.5 to 300 mg of active compound, a suspending/viscosity agent, sweetener, flavor, buffer, and optionally containing flavor enhancer, wetting agent, antimicrobial agent and color or a coloring agent for foodstuffs. There is also disclosed a process for preparing the above-described pharmaceutical formulation and use thereof for treating immunosuppressive diseases, inflammatory diseases, proliferative diseases, viral diseases and psoriasis.
机译:在本发明中,公开了高剂量,干法制粒的麦考酚酸酯或麦考酚酸的含水颗粒的口服悬浮液,其包含7.5至300mg的活性化合物,悬浮/粘度剂,甜味剂,调味剂,缓冲剂,并且任选地包含调味剂增强剂,润湿剂,抗微生物剂和着色剂或用于食品的着色剂。还公开了制备上述药物制剂的方法及其在治疗免疫抑制性疾病,炎性疾病,增生性疾病,病毒性疾病和牛皮癣中的用途。

著录项

  • 公开/公告号CZ301771B6

    专利类型

  • 公开/公告日2010-06-16

    原文格式PDF

  • 申请/专利权人 SYNTEX (U.S.A.) LLC.;

    申请/专利号CZ20020001625

  • 申请日1994-09-27

  • 分类号A61K9/107;A61K9/16;A61K9;A61K9/10;A61K31/34;A61K31/365;A61K31/535;A61K31/5377;A61K47/24;A61K47/36;A61K47/38;A61P17/06;A61P29;A61P31;A61P31/12;A61P35;A61P37;A61P37/06;

  • 国家 CZ

  • 入库时间 2022-08-21 18:47:08

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