Clostridium difficile is an important pathogeny of antibiotic -associated diarrhea in hospitalized patients. Recently ,the emergence of hypervirulent clostridium difficile , which result in an increased incidence and severity of clostridium difficile infection ,is becoming a new threat. Diagnosis of clostridium difficile infection can be made according to clinical manifestation and laboratory data . Rationally use of antimicrobial drugs is the most effective way to minimize the risk of infection . Besides, nosocomial infection control measures should be improved to reduce infection.%艰难梭菌是住院患者抗生素相关性腹泻的重要病因.近年来,由于艰难梭菌高毒力株的出现,导致感染人数明 显增多,疾病严重程度增加,已成为一种新的威胁.艰难梭菌感染(clostridium difficile infection,CDI)的诊断应结合临床表现 和实验室检查两方面.合理使用抗菌药物是减少 CDI 最根本有效的方法,另外,应加强院内感染控制措施以控制感染的传 播.
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