Objective: To confirm the pathogenesis and diagnosis of pediatric Fisher's syndr ome.Methods: Clinical manifestations and Cerebrospinal fluid (CSF) were compared and studied in 22 patients diagnosed as Fisher's syndrome.Results:Twenty- two cases of Fisher's syndrome both had the characteristics of ophthalmoplegia and cerebella ataxia,and had different degrees of incomplete fl accid paralysis in the ar ms and legs. In about half of 22 cases, the CSF showed divergence phenomenon of the protein and cell. Conclusion: Fisher's syndrome is a specific or variant type of AIP involving the cranial nerves, in which the cerebellar ataxia is taken as a main symptom and sign .%目的:进一步明确小儿Fisher氏综合征的病因及诊断标准。方法: 对22例小儿Fisher氏综合征的临床表现、脑脊液进行对比研究。结果:22例患儿均以眼肌 麻痹和小脑共济失调为主征,伴有肢体不同程度的不完全的弛缓性瘫痪,约半数以上病儿脑 脊液出现蛋白、细胞分离现象。结论:Fisher氏综合征是急性感染性神经根神经炎(AIP)一 种 特殊型或变异型,是以小脑共济失调为主的颅神经受损的AIP。
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