胸腔镜解剖性肺段切除术治疗ⅠA期非小细胞肺癌的疗效及对患者肺功能的影响

摘要

目的 探讨胸腔镜解剖性肺段切除术治疗ⅠA期非小细胞肺癌的疗效及对患者肺功能的影响.方法 收集本院自2016年8月至2018年9月收治的64例ⅠA期非小细胞肺癌患者,按手术方式分为观察组与对照组各32例.观察组给予胸腔镜解剖性肺段切除术治疗,对照组给予肺叶切除术治疗,比较两组治疗效果.结果 观察组术中出血量、胸腔置管引流量、胸腔置管引流时间及住院时间均少于对照组(P＜0.05),两组手术时间、淋巴结清扫个数比较差异无统计学意义(P＞0.05);术后1d、2d,两组CRP水平均较术前明显提升,但观察组明显低于对照组(P＜0.05);术后3个月,两组FVC、FEV1均较术前降低,但观察组均高于对照组(P＜0.05);两组术后并发症总发生率比较差异无统计学意义(9.38％比12.50％,P＞0.05).结论 胸腔镜解剖性肺段切除术治疗ⅠA期非小细胞肺癌具有微创的特点,可缩短患者病情康复所需时间,保护肺功能.%Objective To investigate the effect of thoracoscopic anatomical segmentectomy on stage ⅠA non-small cell lung cancer (NSCLC) and its effect on pulmonary function.Methods 64 patients with stage ⅠA non-small cell lung cancer admitted to our hospital from August 2016 to September 2018 were divided into observation group and control group,32 cases in each group.The observation group was treated with thoracoscopic anatomical segmentectomy,while the control group was treated with lobectomy.The therapeutic effects of the two groups were compared.Results The bleeding volume,drainage volume,drainage time,and hospitalization time in the observation group were less than those in the control group (P＜0.05);there were no statistically significant differences in operation time and the number of lymph node dissection between the two groups (P＞0.05).On the 1st and 2nd days after operation,CRP levels in the two groups were significantly higher than those before operation,but those in the observation group were significantly lower than those in the control group (P＜0.05).At 3 months after operation,the FVC and FEV1 of the two groups were lower than those before the operation,but those in the observation group were higher than those in the control group (P＜0.05).There was no statistically significant difference in the total incidence of complications between the two groups (9.38％ vs.12.50％,P＞0.05).Conclusion Thoracoscopic anatomical segmentectomy for stage ⅠA non-small cell lung cancer is minimally invasive,which can shorten the recovery time of patients and protect lung function.