目的观察两种中药方剂联合甲氨喋呤（MTX）治疗异位妊娠的作用。方法未破裂异位妊娠，根据不同中药方剂分为A、B组：A组30例，采用治疗宫外孕中药方剂Ⅰ号联合MTX 50 mg 单剂量注射；B组30例，采用治疗宫外孕中药方剂Ⅱ号联合MTX 50 mg 单剂量注射。结果 A、B组成功率分别为90.％、83.33％。2组比较无差异。但A组疗程成功率明显高于B组，且血β-HCG下降时间（d）A组：（19±5）；B组(26±5)。血β-HCG恢复正常时间明显缩短，（P<0.05）。B组妊娠包块吸收时间明显缩短，差异有统计学意义（P<0.05）。结论宫外孕中药方剂Ⅰ号联合MTX单次用药较宫外孕中药方剂Ⅱ号联合MTX单次用药β-HCG下降速度快，但后者妊娠包块吸收快。较MTX单次用药，剂量较小，相对不良反应轻。%Objective To observe the effect of two kinds of Chinese herbal medicine combined with methotrexate ( MTX ) in the treatment of ectopic pregnancy. Methods According to the different prescription of traditional Chinese medicine,60 cases with unruptured ectopic pregnancy, were divided into two groups:group A 30 cases, were treated with traditional Chinese medical herbs ( referred to as ectopic pregnanc y) and MTX 50 mg single dose intramuscular injection;30 cases in group B, treated ectopic pregnancy prescription ( referred to as EPII ) combined with MTX 50 mg single dose intramuscular injection. Results Success rates of group A, B were respectively 90.00%, 83.33%. There had no significant difference between two groups ( P>0.05 ). But one course of treatment success rate of group A was higher than that in group B, And the bloodβ-HCG fall time (d) of A group:(19 ± 5);(26 ± 5) in group B. The bloodβ-HCG recovery time shortened obviously, (P<0.05). there were signiifcant differences. Gestation mass absorption time obviously shortened in group B, there were significant difference(P<0.05). Conclusion β -HCG decrease faster using ectopic pregnancyⅠcombined with MTX single drug than EPII combined with MTX single dose of , but the latter pregnancy bag piece fast absorption. MTX is only a single dose, low dose, relatively mild side effects.
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