针刺治疗变应性鼻炎的系统评价

摘要

Objective To evaluate the efficacy and safety of acupuncture therapy for the treatment of allergic rhinitis (AR) based on a systematic literature review. Methods Reports of randomized controlled trials (RCTs) about acupuncture treatment for AR were collect from the following databases, such as PubMed, CNKI and so on, by means of computer retrieval. Trial screening, data collection and quality assessment of RCTs were conducted according to the established inclusive and exclusive criteria. Then, data from the included trials was analyzed by RevMan 5.0 Software for further assessment. Results A total of 11 clinical studies, including 1805 patients, met the inclusive criteria of the review for Meta-analysis. Results of Meta-analysis showed that the efficacy of acupuncture treatment was superior to that of sham treatment in reducing the integral of nasal symptoms, and also superior to that of chemical drugs in the effective rate, score-reducing of nasal symptoms, but was not better than chemical drugs in reducing serum level of IgE. Qualitative analysis showed that acupuncture therapy combined with conventional therapy can effectively improve the quality of life among patients with allergic rhinitis. In addition, it was shown that acupuncture therapy was safe for the treatment of allergic rhinitis as well, with no serious adverse effects occurred. Conclusion It is shown based on current evidences that acupuncture can improve the clinical efficacy in the treatment of AR, especially in improving nasal symptoms and reducing adverse effects of routine therapies. However, it is needed to carry out more comprehensively designed randomized controlled clinical trials with larger sample and high quality in methodology to provide more reliable evidences for confirming the efficacy and safety further in this field.%目的 评价针刺治疗变应性鼻炎的疗效和安全性.方法 计算机检索国内外相关数据库,收集针刺治疗变应性鼻炎的随机对照试验(RCTs).按标准筛选研究报告、提取资料并评价证据质量,而后采用RevMan5.0软件进行统计分析.结果 共纳入11个临床研究报告,共计1805例患者进行Meta分析.结果显示,在降低鼻部症状积分方面,针刺疗效优于假针刺,有效率及鼻部症状积分改善均优于西药,但降低血清IgE水平不甚理想.针刺配合常规治疗能有效提高患者生活质量且无明显不良反应.结论 证据显示,针刺可减轻变应性鼻炎症状,提高疗效,但还需更多的大样本临床随机对照研究进行验证.