首页> 外文学位 >Evaluation of small bowel lumen friction forces for applications in in vivo robotic capsule endoscopy.
【24h】

Evaluation of small bowel lumen friction forces for applications in in vivo robotic capsule endoscopy.

机译:小肠管腔摩擦力的评估,用于体内机器人胶囊内窥镜检查。

获取原文
获取原文并翻译 | 示例

摘要

To optimize the design of a robotic capsule endoscope (RCE) capable of exploring and delivering targeted medical therapy to the gastrointestinal tract, it is necessary to quantify the mechanical properties of the aforementioned environment. This research aims to empirically determine a coefficient of friction (COF) between the small bowel lumen and several potential RCE materials and to study how the friction response varies with velocity and contact area along the length of the bowel, specifically when eliminating edge effects from the testing coupon (sled).;To obtain friction force measurements, a novel tribometer was designed and experiments were conducted to measure the friction on the small bowel lumen surface as a function of sled speed, material, contact area, presence of a leading edge and in situ versus in vitro conditions. The friction forces ranged from 0.001 N to 0.06 N under these conditions. A dry friction model was used to extract a COF from the measured forces and COF values ranged from 0.0004 to 0.05. The results show that the COF increases with increasing sled velocity. Contact between polydimethylsiloxane (PDMS) and the intestinal lumen yields a larger COF than that of stainless steel or polycarbonate. The COF does not demonstrate significant changes with pressure, but does respond to changes in contact area and weight, although the complexities of that relationship were not thoroughly investigated in this research. The results also indicate that by eliminating edge effects, the friction force between a stainless steel sled and the small bowel lumen surface is decreased. The average COF for in situ testing was found to be slightly lower than in vitro tests. These results can be incorporated into the design and control of an RCE to improve mobility within the gastrointestinal tract.
机译:为了优化能够探索并向胃肠道输送靶向药物的机器人胶囊内窥镜(RCE)的设计,有必要对上述环境的机械性能进行量化。这项研究的目的是根据经验确定小肠腔与几种潜在的RCE材料之间的摩擦系数(COF),并研究摩擦响应如何随速度和接触面积沿肠的长度变化,特别是在消除肠壁边缘效应时。为了获得摩擦力的测量值,设计了一种新型的摩擦计,并进行了实验,以测量小肠腔表面上的摩擦力,该摩擦力是滑动速度,材料,接触面积,前缘和原位与体外条件。在这些条件下,摩擦力为0.001 N至0.06N。使用干摩擦模型从测得的力中提取COF,并且COF值的范围为0.0004至0.05。结果表明,COF随着雪橇速度的增加而增加。聚二甲基硅氧烷(PDMS)与肠腔之间的接触会产生比不锈钢或聚碳酸酯更大的COF。 COF并没有显示出压力的显着变化,但确实对接触面积和重量的变化做出了响应,尽管在本研究中并未对这种关系的复杂性进行彻底研究。结果还表明,通过消除边缘效应,减少了不锈钢雪橇与小肠腔表面之间的摩擦力。发现原位测试的平均COF略低于体外测试。这些结果可以并入RCE的设计和控制中,以改善胃肠道内的活动性。

著录项

  • 作者

    Lyle, Allison B.;

  • 作者单位

    University of Colorado at Boulder.;

  • 授予单位 University of Colorado at Boulder.;
  • 学科 Engineering Biomedical.;Biophysics Biomechanics.
  • 学位 M.S.
  • 年度 2012
  • 页码 96 p.
  • 总页数 96
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号