Introduction

摘要

Data generated by novel imaging technologies such as optical tomography are complex to analyze due to the inherent scattering of light through anatomical systems. Cross validation and direct comparison with established methods in other imaging modalities are especially challenging. There is critical need for new computational techniques to provide rapid, accurate and cost-effective means for quantification and characterization of such data, either independently or integrated with other modalities. These computational methods will enable faster acceptance of novel imaging modalities into viable clinical and/or pre-clinical systems. The applications are diverse and range from imaging at the cellular level to the whole body while incorporating molecular, functional and anatomical information.