Comparative investigations of structure and absorptive capacity of nano- and microsized magnetic-operated particles for their application in medicine and biology

摘要

For the first time, the comparative investigations of structure and sorption efficiency of nano- and microsized magnetic-operated particles in respect to both the antigen and virus hepatitis B and also to the substance-markers (low-, middle- and highmolecular substances) were carried out. The sorption efficiency of magnetic particles: magnetite (Fe_3O_4), cobalt-ferrite (CoFe_2O_4), composite ferro-carbon (FeC) to the substances of different molecular weight was evaluated in vitro experiments. The high absorptive capacity to low- and highmolecular substance-markers has been observed for microsized composites of FeC. Absorptive capacity of the nanosized Fe_3O_4 and CoFe_2O_4 particles to the substance-markers was low. But the nanosized Fe_3O_4 and CoFe_2O_4 particles had a good absorptive capacity to virus of hepatitis B and its antigen (HBsAg). The sorption efficiency results of nano- and microsized magnetic particles correlate with the structure of their surface.