Characterization of the suppressive effects of extremely-low-frequency electric fields on a stress-induced increase in the plasma glucocorticoid level in mice

摘要

Recently, we found that in male BALB/c mice, the immobilization-induced increase in serum glucocorticoid (GC) was reduced by exposure to an electric flied (EF) of 50 Hz, when the voltage was applied via the upper electrode of a parallel plate electrode system. This effect was dependent on both intensity (kV/m) and exposure time. The present study aimed to assess the anti-stress effect of the EF in 3 scenarios with the experimental system: the use of either 50 or 60 Hz, which are the standard power frequencies in most regions; varying levels of environmental brightness; complete or partial shielding of the mouse from the EF. We compared the GC levels among control, EF-alone, immobilization-alone, and co-treatment groups.