Study on Physicochemical Properties of Tilapia Skin Collagen Scaffold Cross-linked by EDC

摘要

In order to improve physicochemical properties of Tilapia skin collagen (TSC), l-ethyl-3-(3-dimethyl amino-propyl)-carbodiimide (EDC) was used as a cross-linking agent for TSC matrices. The difference in physicochemical properties between cross-linked and uncross-linked TSC was characterized by measuring shrinkage temperature, water uptake and anti-enzyme effect. The results indicated that, after the cross-linking, the thermal stability was increased;;the anti-enzyme effect was improved obviously. It is thus concluded that the EDC cross-linking greatly improve the physicochemical properties of TSC.