THE MECHANISMS OF ANTICOAGULANT ACTIVITY OF THE GLYCOCONJUGATES ISOLATED FROM CONYZA CANADENSIS L. BY THE ULTRASOUNDS ASSISTED EXTRACTION

摘要

The Canadian horseweed (Erigeron canadensis L.) is a common, annual herbal plant grows especially in the northern climate zone [1]. Flowering parts of E. canadensis are very often utilized in folk medicine [2], due to presence of various compounds, such as essential oils, tannins and flavonoids [3,4]. The preparations from horseweed are used as diuretic, tonic, antifungal and astringent agents. Our research team have obtained and investigated from this plant the polyphenolic glycoconjugates, according to the already described multi-step isolation process [5], with application of the ultrasounds assisted extraction (UAE) in the alkaline environment. The hot water extraction, even in alkaline condition, consumes time and solvents, therefore usage of UAE, due to the specific phenomenon such as microcavitation forces, can radically decrease time of the whole process.