A proposal for the use of propofol sedation by a non- anesthesiologist in ESD for early gastric cancer.

摘要

Sedation is important for the success and the quality of endoscopic submucosal dissection (ESD) for gastric cancer, and propofol is a promising anesthetic. In this study, we evaluated the serious adverse effects (SAE) and treatments of its use in our clinic. 409 ESD patients with propofol sedation were enrolled. There were 21 cases (5.1%) with SAE (hypotension, bradycardia and de-saturation). The risk factors for SAE were male and procedure time of ESD. We estimated the SAE and treatment for it in this study. We propose that ESDs using propofol sedation will be able to take place safely if a fulltime on staff doctor can be determined to administer the sedation, even if the doctor is not an anesthesiologist.