PHYLOGENETIC ANALYSIS OF AUSTRIAN PRRSV FIELD ISOLATES

摘要

Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically devastating diseases in swine industry and was first recognized in the US in 1987 and in Europe in 1990. However, in Austria the first outbreak of PRRS was diagnosedon a farm in Upper Austria in 1993. Meanwhile, antibodies against EU and US isolates of PRRS virus (PRRSV) as well as viruses themselves have been found in Austria, although US based live vaccines are not licensed in Austria. The objective of this studywas to characterize PRRSV field isolates recovered from Austrian pigs with clinical symptoms of PRRS by sequencing open reading frame (ORF) 5, that encodes for the major envelope glycoprotein and is known to be the most variable region of PRRSV genome.