CMOS-Based Bio Sensors - Introduction to DNA Microarrays

摘要

Since its invention in the 1980's and with the advent of the Human Genome Sequencing Project, DNA microarrays have helped to reshape and expand the fields of genetics and molecular biology. Their uses span the spectrum of gene expression, genotyping and resequencing applications from academic research through clinical and point-of-care diagnostics. Additionally, it has become an indispensable part of the pharmaceutical industries drug discovery toolkit. This presentation will discuss various aspects of microarrays including: an introduction to the various types of DNA microarrays; common methods of microarray fabrication; as well as their use in a variety of biological applications across various market segments. We will also explore recent developments in the field which are expanding the current limits of information density, detection methods and applications.