Effects of Astragalus Polysaccharides on Immune Functions of Erythrocyte of Chickens Infected with IBDV

摘要

One hundred and sixty Haline white chickens at 25 days old, negative reaction to the antibody of infectious bursal disease virus (LBDV), were randomly divided into four groups (40 each group). Chickens in group 2 to 4 were infected with 0.3ml IBDV by nasal drip and eye droppings at 26 days old. Chickens in group 1 and 2 were not injected with Astragalus polysaccharide (APS). Each chicken in group 3 and 4 were respectively injected with 5 mg and 10 mg APS per day from 26 to 31 days old. The blood samples of 1 to 3 milliliters were taken from heart at 21, 29, 32, 35 and 38-day old, and erythrocyte-C3b receptor rosette rate (E-C3b RR), erythrocyte-C3b immune complex rosette rate (E-ICRR), erythrocyte rosette forming enhancing rate (ERER) and erythrocyte rosette forming inhibitory rate (ERIR) were measured. The results showed that E-C3bRR and ERER significantly declined in chickens infected with IBDV (p<0.01), E-C3b RR, E-ICRR and ERER in group3 and 4 treated with APS were higher than that in group 1 and 2 (p<0.01), the ERIR in group 3 and 4 are similar to that in group 1. The results suggest that the immunological function of chicken erythrocytes declines after infected with IBDV and APS obviously enhances the immunological function of chicken erythrocytes.