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Method of predicting Diabetic Foot Ulcer Recurrence or Prognostics using Specific Methylation of gene

机译:利用基因特异性甲基化预测糖尿病足溃疡复发或预后的方法

摘要

The present invention relates to a biomarker for predicting diabetic foot ulcer recurrence or prognosis according to specific methylation of one or more genes selected from the group consisting of MORN1 , NCOR2 , and LINC00504 . The present invention identifies a specific pattern of diabetic foot ulcer recurrence or prognosis, discovers major biomarkers that explain the pattern through machine learning for genetic data, and uses the blood analysis-based clinical biomarker for diabetic foot Not only can it predict ulcer recurrence or prognosis, but it can also be used for the development of mechanisms for preventing or treating diabetic foot ulcers in the future. It is possible to build a system that can preemptively control.
机译:本发明涉及根据从MORN1、NCOR2和LINC00504组成的组中选择的一个或多个基因的特定甲基化来预测糖尿病足溃疡复发或预后的生物标记物。本发明识别糖尿病足溃疡复发或预后的特定模式,通过遗传数据的机器学习发现解释该模式的主要生物标记物,并且使用基于血液分析的糖尿病足临床生物标记物不仅可以预测溃疡复发或预后,但它也可以用于未来预防或治疗糖尿病足溃疡的机制的开发。建立一个能够抢占控制的系统是可能的。

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