METHOD FOR DIAGNOSING OR PREDICTING HEPATOCELLULAR CARCINOMA USING DNA METHYLATION CHANGES OF INTRAGENIC CPG ISLAND INVOLVED IN HEPATOCELLULAR CARCINOMA-SPECIFIC GENE EXPRESSION

摘要

The present invention relates to a method for predicting or diagnosing hepatocellular carcinoma (HCC) using methylation changes of intragenic CpG island (intragenic CGI) involved in HCC-specific gene expression and, more specifically, to a method for predicting or diagnosing HCC using DNA methylation changes of intragenic CGI involved in the epigenetics during the HCC occurring process. According to the present invention, patient-customized treatments for HCC are possible based on association of DNA methylation changes of intragenic CGI involved in the epigenetics during the HCC occurring process, and races, sexes, ages and virus by patient group.;COPYRIGHT KIPO 2017