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Marker predicting liver cancer recurrence in patients with liver transplantation prescription and uses thereof

机译:标记预测肝移植处方患者肝癌复发和其用途

摘要

The present invention relates to a marker for predicting the prognosis of liver cancer recurrence in liver cancer patients, and more specifically, an RNA marker related to the amount of immunoregulatory cells for suppressing the inflammatory response and inflammatory response appearing in liver transplantation surgery patients or preliminary liver transplantation patient groups. It relates to use as a marker for predicting relapse prognosis. The present inventors found a change in the expression pattern of a gene related to liver cancer recurrence in a patient who was prescribed liver transplantation surgery, and found that the gene can be a predictive marker for liver cancer recurrence prognosis. The marker according to the present invention is a liver transplantation It is expected that it will help the management and treatment of liver cancer patients who have been prescribed this by predicting the recurrence of liver cancer.
机译:本发明涉及一种用于预测肝癌患者肝癌复发预后的标志物,更具体地,与用于抑制肝移植手术患者的炎症反应和炎症反应的免疫调节细胞量相关的RNA标记物相关的RNA标志物相关 肝移植患者组。 它涉及用作预测复发预后的标记。 本发明人发现了与处方肝移植手术的患者肝癌复发相关的基因表达模式的变化,发现基因可以是肝癌复发预后的预测标志物。 根据本发明的标记是肝移植预期,它将有助于通过预测肝癌的复发来帮助肝癌患者的管理和治疗。

著录项

  • 公开/公告号KR102338677B1

    专利类型

  • 公开/公告日2021-12-10

    原文格式PDF

  • 申请/专利权人 한양대학교 산학협력단;

    申请/专利号KR20190054157

  • 发明设计人 남진우;윤상호;

    申请日2019-05-09

  • 分类号C12Q1/6886;G01N33/574;

  • 国家 KR

  • 入库时间 2022-08-24 22:45:55

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