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Lipid Particle Formulations for Delivery of RNA and Water-Soluble Therapeutically Effective Compounds to a Target Cell

机译:脂质颗粒制剂用于将RNA和水溶性治疗有效化合物递送至靶细胞

摘要

The present invention relates to lipid particles comprising at least one cationic lipid, at least one water-soluble therapeutically effective compound and RNA. Further, the present invention relates to a pharmaceutical composition comprising such particles. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the particles.
机译:本发明涉及包含至少一种阳离子脂质,至少一种水溶性治疗性有效化合物和RNA的脂质颗粒。 此外,本发明涉及包含这种颗粒的药物组合物。 所述药物组合物可用于诱导免疫应答。 它在涉及抗原的疾病的预防和/或治疗方法中也是有用的。 此外,本发明涉及制备颗粒的方法。

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