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Pharmacokinetic analysis method, pharmacokinetic analysis device and program

机译:药代动力学分析方法,药代动力学分析装置和程序

摘要

We propose a pharmacokinetic analysis method and the like that can easily analyze changes in the pharmacokinetics of the patient in response to changes in the patient's physiological function. Using the input physiological function of the patient, the individual pharmacokinetic calculation unit 21 calculates the individual pharmacokinetic value of the patient using a mathematical model, and the group pharmacokinetic acquisition unit 25 calculates the group pharmacokinetic value of the group to which the patient belongs. Get The coefficient of variation calculation unit 29 calculates the coefficient of variation from the personal pharmacokinetic value and the population pharmacokinetic value. The population change pharmacokinetic acquisition unit 41 obtains a change in the average pharmacokinetic value of the population in response to the input change in physiological function. The patient change pharmacokinetic system dark part 45 takes advantage of the fact that the variation coefficient is constant even if the physiological function changes, and uses the change in the average pharmacokinetic value of the population and the change in the individual pharmacokinetic value of the patient using the change coefficient. Get
机译:我们提出了一种药代动力学分析方法等,可以响应患者生理功能的变化,容易分析患者药代动力学的变化。使用患者的输入生理功能,各个药代动力学计算单元21使用数学模型计算患者的单独药代动力学值,并且组药代动力学拍摄单元25计算患者所属的组的组药代动力学值。获得变异系数计算单元29计算与个人药代动力学价值和人口药代动力学值的变化系数。人口改变药代动力学习得单元41响应于生理功能的输入变化获得群体的平均药代动力值的变化。患者改变药代动力学系统暗部45利用了变化系数即使生理功能的变化,并且使用群体平均药代动力值的变化以及患者使用的单独药代动力值的变化变化系数。得到

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