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PHARMACOKINETIC ANALYSIS METHOD, PHARMACOKINETIC ANALYSIS DEVICE, AND PROGRAM
PHARMACOKINETIC ANALYSIS METHOD, PHARMACOKINETIC ANALYSIS DEVICE, AND PROGRAM
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机译:药代动力学分析方法,药代动力学分析装置和程序
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摘要
The purpose of the present invention is to provide a pharmacokinetic analysis method and the like, whereby a pharmacokinetic change in a patient can be easily analyzed in response to a change in a physiological function of the patient. An individual pharmacokinetics calculation unit 21 calculates an individual pharmacokinetic value of a patient by using an entered physiological function of the patient and a mathematical model, and a population pharmacokinetics acquisition unit 25 obtains a population pharmacokinetic value of a population to which the patient belongs. A variation coefficient calculation unit 29 calculates a variation coefficient from the individual pharmacokinetic value and the population pharmacokinetic value. A change-in-population-pharmacokinetics acquisition unit 41 obtains a change in the average pharmacokinetic value of the population in response to the change in the entered physiological function. A change-in-patient-pharmacokinetics calculation unit 45 obtains, by taking advantage of the fact that the variation coefficient remains constant even when the physiological function has changed, a change in the individual pharmacokinetic value of the patient by using the change in the average pharmacokinetic value of the population and the variation coefficient.
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