Miso prostol dispersible tablets

摘要

To provide an alternative route of administration of a solid pharmaceutical formulation comprising misoprostol or a pharmaceutically acceptable salt thereof.SOLUTION: The present invention concerns a dispersible tablet comprising misoprostol or a pharmaceutically acceptable salt thereof, allowing an administration form selected from among sublingual, oral and vaginal administration. The tablet is suitable in particular for cervical ripening and labor induction and for preventing and/or treating post-partum and post-abortive bleeding. The tablet provides a mean terminal half-life (t1/2) of less than 0.60 hours, preferably less than 0.55 hours, further preferably less than 0.50 hours, and preferably less than 0.45 hours.SELECTED DRAWING: Figure 2B