METHODS OF MODULATING M2 MACROPHAGE POLARIZATION AND USE OF SAME IN THERAPY

摘要

A method of treating a disease or disorder that can benefit from increasing an M2/M macrophage ratio in a subject in need thereof is provided. The method comprising: (a) culturing basophils in the presence of IL33 and/or GM-SCF; and (b) administering to the subject a therapeutically effective amount of the basophils following the culturing, thereby treating the disease or disorder that can benefit from increasing an M2/M1 macrophage ratio in the subject.