Cell growth promoter, cell care promoting agent for promoting cell proliferation, supplement for promoting cell proliferation, food intake promoting cell proliferation, cosmetic promotion promoting agent, method for producing active component of cell growth promoting agent and method for mixing proteoglycans derived from salmon nasal cartilage

摘要

PROBLEM TO BE SOLVED: To provide cell growth promoting agents activating signaling factor Erk1/2.SOLUTION: The present invention relates to a proteoglycan derived from salmon nasal cartilage having a molecular structure which is defective for G3 domain. The proteoglycan activate cell growth signaling factor Erk1/2 through sugar chain part Cs, and effectively promotes the cell growth of a human skin fibroblast. The proteoglycan is a cell growth promoting agent useful for preventing skin roughness, wrinkle, decreased elasticity, decreased joint function, and the like, as well as is available as a skin care agent, a supplement, a food and drink, and a cosmetic.SELECTED DRAWING: Figure 1