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Biomarkers for prediction of response to neoadjuvant chemoradiation therapy in rectal cancer

机译:用于预测直肠癌对新辅助化学疗法的反应的生物标志物

摘要

The present invention relates to a biomarker for predicting the response to anticancer radiotherapy selected from the group consisting of CAMP (human cathelicidin antimicrobial peptide), LPCAT2 (Lysophosphatidylcholine acyltransferase 2) and AKR1B1 (Aldo-keto reductase family 1, member B1). Specifically, a composition for predicting response to anticancer radiotherapy; Prediction kit; It relates to a method of providing information for prediction. By using the biomarker of the present invention, the presence or absence of a reaction to anticancer radiation therapy of a rectal cancer patient can be predicted before surgery, which can greatly help in determining a treatment policy for a rectal cancer patient.
机译:本发明涉及一种用于预测从营养营(人疗法型抗微生物肽),LPCAT2(溶血磷脂酰胆碱酰基转移酶2)和AKR1B1(Aldo-Keto还原酶第1系列)和AkR1B1(Aldo-keto还原酶1,成员B1)组成的抗癌放射疗法的抗冒犯放疗响应的生物标志物。具体地,用于预测对抗癌放疗反应的组合物;预测套件;它涉及一种提供预测信息的方法。通过使用本发明的生物标志物,可以在手术前预测到直肠癌患者的抗癌辐射治疗的反应的存在或不存在,这可以有助于确定直肠癌患者的治疗政策。

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