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HIGH AFFINITY MONOCLONAL ANTIBODIES (MABS) AGAINST CELL SURFACE EXPRESSED HUMAN CARBONIC ANHYDRASE IX (HCA-IX), AND USES THEREOF
HIGH AFFINITY MONOCLONAL ANTIBODIES (MABS) AGAINST CELL SURFACE EXPRESSED HUMAN CARBONIC ANHYDRASE IX (HCA-IX), AND USES THEREOF
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机译:对细胞表面的高亲和力单克隆抗体(mAb)表达人碳酸酐酶IX(HCA-IX)及其用途
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摘要
The present invention provides a set of Carbonic Anhydrase-IX monoclonal antibodies (CA-IX mAbs) that bind with high affinity to cell-surface expressed hCA-IX and has enzyme inhibiting characteristics. These mAbs have the potential to become the next biologics for the treatment of renal and possibly other types of cancer.
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