8-CHLORO-5,6,7,8-TETRAHYDROQUINOLINE-2-ONE AND 8-BROMO-5,6,7,8-TETRAHYDROQUINOLINE-2-ONE, THEIR HYDROCHLORIDES AND HYDROBROMIDES, AND PROCESS FOR THEIR PREPARATION

摘要

8-Chloro-5,6,7,8-tetrahydro-2-quinolone and 8-bromo-5,6,7,8-tetrahydro-2-quinolone, the hydrochloride or hydrobromide thereof and their manufacture by reacting 3,4,5,6,7,8-hexahydro-2-quinolone with chlorine or bromine in an inert solvent at 10 DEG to 50 DEG C. with heating of the reaction mixture to 60 DEG to 80 DEG C. after the halogen addition.