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Process for the preparation of pharmaceutical compositions containing lisostafina and methods for use of lisostafina in the treatment of bovine mastitis and other infeccoes estafilococais
Process for the preparation of pharmaceutical compositions containing lisostafina and methods for use of lisostafina in the treatment of bovine mastitis and other infeccoes estafilococais
Compsn. (A) for killing staphylococci comprises lysostaphin (I) and synergist(s) from penicillin, synthetic penicillins, other antibiotics, chelating agents, mild surfactants and other membrane active agents, in amts. effective to kill staphylococci. Preventing bovine mastitis comprises dipping teats in a soln. (B) of 0.01-10.0 mcg/ml of (I) in a suitable carrier, before and after each milking. The compsn. (A) and teat dip soln. (B) may also comprise lysozyme and mutanolysin.
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机译:Compsn。 (A)用于杀死葡萄球菌的药物包括溶菌素(I)和来自青霉素,合成青霉素,其他抗生素,螯合剂,温和表面活性剂和其他膜活性剂的增效剂。有效杀死葡萄球菌。预防牛乳腺炎包括将乳头浸入锡罐中。 (B)在每次挤奶之前和之后在合适的载体中的0.01-10.0 mcg / ml(I)。该compsn。 (一)乳头浸液。 (B)也可以包含溶菌酶和变溶菌素。
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