The consensus sequences of the origin of replication of DNA mamìfero or human.Process for the control of initiation of DNA for the maintenance of constructos of plasmìdeo circular and of DNA suitable

摘要

"Sequence of consensus of the origin of replication of DNA mamu00ecfero or human, the process for the control of initiation of DNA replication mamu00ecfero, use of a DNA sequence.Proteu00ecna which binds to the DNA replication of mamu00ecfero which generates the sequence of SEQ ID No: 1, consensus, and the process of inhibition of DNA replication in vitro or in vivo.The present invention relates to a sequ00b3u00eancia consensus of origin of replication of DNA in mammal or human DNA consists of a sequ00b3u00eancia mammal or human consists of SEQ.u00b3u00eancia selected the group consisting of cctmdawksgbytsmaawywbcmtyttrscaaattcc (SEQ ID No: 1); awmtwaakrawrwwkkdavwwwgakrwwkwvwhrass acmdwkaaktwkggwtwarrywkgrkmwwtwakawsda (SEQ ID takwwwkdakwkmwrkttIn: 4).A process for the control of initiation of DNA replication of mammal which comprises the steps of: (a) insert a sequ00b3u00eancia consensus coding of a sequ00b3u00eancia of this invention juntamenYou with a DNA fragment to form a vector capable of expression of the DNA fragment; (b) introducing the vector of the step (a) in mammalian cells in vitro.