DNA or rna sequence, putative promoter specific for t. cruzi, expression cassette, vector, cell, antigenic determinant or epitope of the ptc40 protein, monoclonal or polyclonal antibodies, reagent, and process for the detection and / or monitoring of trypanosoma cruzi infection, process for preparing an antigenic determinant, pharmaceutical composition, and, use of a pharmaceutical composition

摘要

"DNA OR RNA SEQUENCE, USE OF A SPECIFIC PUTATIVE PROMOTER FOR T.CRUZI ALONG WITH THE SEQUENCE, EXPRESSION CASSETTE, VECTOR, CELL, DETERMINANT ANTIGENIC OR EPYPE OF THE PTC40 PROTEIN, MONOCLONIC, PROCEDURAL AND POLYCONAL ANTIBODIES, PROCEDURAL, POLYCONAL, PROCEDURAL OR DETECTION AND / OR MONITORING OF TRYPANOSOMA CRUZI INFECTION, PROCESS TO PREPARE AN ANTIGENIC DETERMINANT, PHARMACEUTICAL COMPOSITION, AND USE OF A PHARMACEUTICAL COMPOSITION ". The nucleotide sequence of Tc40, a gene encoding a new antigenic Trypanosoma cruzi protein called PTc40 is described. The amino acid sequence of PTc40 protein is also described, along with the amino acid sequence of the dominant antigenic epitope of the Ptc40 protein. The Ptc40 protein and the Tc40 gene, or a fragment thereof, modified or otherwise, can be used directly or indirectly for the detection of Trypanosoma cruzi, or for monitoring an infection generated by T. cruzi in men or animals.