首页> 外国专利> An epitope polypeptide comprising a sequence isolated from T. cruzi antigen, DNA, recombinant expression vector, host Cell, Methods for the detection of T.Cruzi, Diagnostic KIT, Pharmaceutical composition, Vaccine and polypeptide in combination

An epitope polypeptide comprising a sequence isolated from T. cruzi antigen, DNA, recombinant expression vector, host Cell, Methods for the detection of T.Cruzi, Diagnostic KIT, Pharmaceutical composition, Vaccine and polypeptide in combination

机译:表位多肽,其包含从克鲁维氏酵母抗原分离的序列,DNA,重组表达载体,宿主细胞,克鲁维氏酵母的检测方法,诊断试剂盒,药物组合物,疫苗和多肽的组合

摘要

Compounds and methods for the detection and prevention of T. cruzi infection have been found in human body and blood, and selective tests have been carried out to detect the infection of T. cruzi in biological samples. On one hand, this request provides a method to detect the infection of T.cruzi in biological samples, including connecting biological samples with sterile organisms (including the epithelium of T.cruzi antigen), Or select more peptides or peptide condensation or monoclonal antibodies to bind to the epithelium of T.cruzi antigen,The presence of the dead body or polypeptide or T. cruzi parasite and monoclonal antibody were detected in biological samples. Another form of polypeptide includes an epilepsy or variant of TCD. In another implementation, additional peptides include a TCD epilepsy and a TCE epilepsy. In another implementation, additional peptides include TCD and PEP-2. In other aspects, a direct request for the provision of a mixed polypeptide includes two or more polypeptides;Each polypeptide includes the epithelium of one T.cruzi antigen, or at least one T.cruzi antigen, and at least one specific delta epilepsy, including TCD epilepsy, TCE epilepsy, PEP-2 epilepsy and its variants. Another aspect of this requirement is aseptic sevroveen, including T. cruzi antigen of epithelioma. Sevroveen, DNA sequence, used to encrypt previous peptides
机译:已经在人体和血液中发现了用于检测和预防克氏锥虫感染的化合物和方法,并且已经进行了选择性测试以检测生物样品中的克氏锥虫感染。一方面,该要求提供了一种检测生物样品中克鲁氏杆菌感染的方法,包括将生物样品与无菌生物(包括克鲁氏抗原的上皮)连接,或选择更多肽或肽缩合或单克隆抗体结合克鲁维酵母抗原的上皮,在生物样品中检测到尸体或多肽或克鲁维寄生虫和单克隆抗体的存在。多肽的另一种形式包括TCD的癫痫或变体。在另一个实施方案中,另外的肽包括TCD癫痫和TCE癫痫。在另一个实施方案中,另外的肽包括TCD和PEP-2。在其他方面,提供混合多肽的直接请求包括两种或更多种多肽;每个多肽包括一种T.cruzi抗原或至少一种T.cruzi抗原的上皮,以及至少一种特异性δ癫痫,包括TCD癫痫,TCE癫痫,PEP-2癫痫及其变种。该要求的另一方面是无菌sevroveen,包括上皮瘤的克氏锥虫抗原。 Sevroveen,DNA序列,用于加密先前的肽

著录项

  • 公开/公告号AR014132A1

    专利类型

  • 公开/公告日2001-02-07

    原文格式PDF

  • 申请/专利权人 CORIXA CORPORATION;

    申请/专利号AR1998P106437

  • 发明设计人

    申请日1998-12-17

  • 分类号C07K14/44;C12N15/30;C12N15/63;C12N1/21;C12N1/19;C12N5/10;G01N33/569;G01N33/543;G01N33/577;A61K39/005;

  • 国家 AR

  • 入库时间 2022-08-22 01:26:23

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