首页> 外国专利> Nucleic Acid molecules from the Genome of 8 types of sen virus (A to H), one of them responsible for cryptogenic hepatitis non a-e, Proteins, Antibodies, Pharmaceutical compositions, vaccines,Diagnostic methods, Solid Phase, knew contains those products.

Nucleic Acid molecules from the Genome of 8 types of sen virus (A to H), one of them responsible for cryptogenic hepatitis non a-e, Proteins, Antibodies, Pharmaceutical compositions, vaccines,Diagnostic methods, Solid Phase, knew contains those products.

机译:来自8种sen病毒基因组的核酸分子(A到H),其中一种负责隐性非a-e型肝炎,蛋白质,抗体,药物组合物,疫苗,诊断方法,固相,都知道包含这些产品。

摘要

The present Invention relates to a Nucleic Acid Molecule refeire represents the Genome of a virus / viral Agent,The Nucleic Acid Molecule possessing at least some and contain at least the following characteristics: an open reading frame (ORF), which encodes a polypeptide that has aAmino Acid Sequence described here,Includes a sequence as described here give Hybrid preferably in restrictive conditions with the complementary Strand of nucleic acid Molecule described here,But not with the complementary Strand of the virus Genome TT; is degenerate with respect to the Molecule of nucleic acid Hybrid is at least 60% identical to the Molecule of acid nuCelico represents the Genome of the virus / viral Agent of the invention; and parts of it can be amplified by PCR using the primers and conditions described here.The Invention further relates to vectors comprising the Nucleic Acid Molecule, DFE methods producior Peptide encoded by the Nucleic Acid Molecule,The virus / viral agents that incorporate a Genome represented by the nucelico acid Molecule and Antibody against these peptides and / or the virus / viral Agent.Additionally, The Invention relates to compositions preferably Pharmaceutical compositions.Reacctivos Diagnostics, vaccines and Diagnostic kits that include using the compounds of the invention.
机译:本发明涉及核酸分子的伪造,其代表病毒/病毒剂的基因组,该核酸分子具有至少一些并且至少包含以下特征:开放阅读框(ORF),其编码具有以下特征的多肽:具有本文所述的氨基酸序列,包括本文所述的序列,优选在限制性条件下使杂种与本文所述的核酸分子的互补链互补,但不与病毒基因组TT的互补链互补;相对于核酸分子是简并的。杂交体与代表本发明病毒/病毒剂的基因组的核酸分子至少60%相同;本发明还涉及包含核酸分子的载体,该核酸是由DFE方法生产的,由核酸分子编码的肽,包含基因组的病毒/病毒剂。此外,本发明涉及组合物,优选药物组合物。Reacctivos诊断,疫苗和诊断试剂盒包括使用本发明的化合物。

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