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Binding partner and method for competitive inhibition of the binding between nef - protein and calmodulin, and means and use in the case of hiv - diseases
Binding partner and method for competitive inhibition of the binding between nef - protein and calmodulin, and means and use in the case of hiv - diseases
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机译:竞争性抑制nef-蛋白与钙调蛋白之间结合的结合伴侣和方法,以及在HIV疾病中的手段和用途
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摘要
The invention relates to binding partners for NEF protein or calmodulin which competitively inhibit the binding between calmodulin and NEF protein, as well as to a method for the intra- and/or extracellular competitive inhibition of binding between NEF protein and calmodulin. According to the method, at least one of the two binding partners is brought into contact with HIV-infected cells. The invention further relates to pharmaceutical preparations containing at least one of these binding partners and to the use of the binding partners in the prevention, diagnosis and/or treatment of HIV-related diseases.
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