BAC-end sequencing STC approach genome sequencing with shotgun The model of software design programming to support automatic and integrated research of whole sequence alignment with BAC-end sequencing STC approach genome sequencing through shotgun method

摘要

PURPOSE: A software design and production model for supporting automation and integration of an entire base order determination research in the BAC-end sequencing and STC approach genome sequencing with shotgun is provided so that data modeling and function constitution for the software design and production can be achieved by automating a research process and integrating data. CONSTITUTION: Research data including a clone, marker and contig must be integrated on the basis of an optimized database for the genome research such as Acedb in order to embody the whole sequencing. In addition, research processes including physical mapping and genetic mapping, sequence analysis processes, and succeeding processes including OSF search and Homology analysis should be organically integrated according to data and user interfaces. Accordingly, models are represented in a strategical model diagram of the genome research, a sequential typical diagram of the respective unit processes, and a cyclic development diagram of a real research cycle, which is appropriate for the whole sequencing research cycle of the BAC-end sequencing and STC approach genome sequencing with shotgun.