Device for the optical control of sequencing of nucleic acid.In particular to control optical reaction steps iteratively to determine a sequence of a nucleic acid by synthesis.Method for controlling optical sequencing of nucleic acid.In particular to control optical reaction steps iteratively to determine a sequence of a nucleic acid by synthesis.Element of the programme for the control of a optical DNA sequencing, medium readable by computer.In which a computer program for controlling optical a DNA sequencing and the use of a portion as a portion of the blocking in the sequencing of DNA

摘要

Summary device for optical control of sequencing of nucleic acid.In particular to control optical reaction steps iteratively to determine a sequence of a nucleic acid by synthesis.Method for controlling optical sequencing of nucleic acid.In particular to control optical reaction steps iteratively to determine a sequence of a nucleic acid by synthesis.Element of the programme for the control of a optical DNA sequencing, medium readable by computer.In which a computer program for controlling optical a DNA sequencing and the use of a portion as a portion of the block in DNA sequencing, the present invention relates to the SequenciEnhanced DNA with the cycling reagent in the grid of wires. The approach of sequencing suggested with which allows the use of a single fluid with no washing stage.Based on the strong optical confinement and the excitation light and the light of the cleavage reaction of sequencing can be read without washing the surface.The sequencing of steps is achieved by the use of nucleotides with locking portions optically clivu00e1veis.After the reading, the incorporated into the nucleotide is unlocked by the light of the cleavage through the same substrate. This ensures that only nucleotides linked to be unblocked.