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Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
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机译:蛋白质,基因及其在双相情感障碍和单相抑郁症的诊断和治疗中的用途
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摘要
The present invention provides methods and compositions for screening, diagnosis and prognosis of BAD, for monitoring the effectiveness of BAD treatment, and for drug development. BAD-Associated Features (DFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides BAD-Associated Protein Isoforms (DPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated DPIs, antibodies immunospecific for DPIs, and kits comprising the aforesaid.
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