A Derivative of 2 - mercapto - Cyclodextrin, its use, a Pharmaceutical composition that comprises a kit to provide neuromuscular blockade and sureversion,And a method for reversal of neuromuscular blockade induced by drugs

摘要

1. The general formula of 6-cyclopropylene glycol derivatives (1): m is 0-7; n is 1-8, M + n = 7 or 8; R is C1-6 tar, which can be replaced by 1-3 groups of Oh, O (CH2) or - phenyl - (CH2) p;O. P is independent 0-4; X is COOH, conhr1, nhr2, so2oh, Po (O H) 2, O (ch2-ch2-o) Q-H, oh, O tetrazol-5-ilo; R1 is h or c1-3 tar; R2 is carboxiphenio; q is 1-3; or salt acceptable for drug use. 6-mercato-cyclohextrina derivatives are very suitable for reversing drug-induced neuromuscular block.