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Library of substances, Process for their Preparation and the use of this library to research active substances substances

机译:物质资料库,其制备过程以及该资料库用于研究活性物质的资料

摘要

Library of substances obtained by reaction of aromatic compounds aldehu00eddricos and / or aldehu00eddricos heteroaromatic compounds and / or aldehu00eddricos aliphatic compounds devoid of Proton acid PCompositions in solution in the presence of a base, with Secondary amines to give compounds of animal,Reaction of these compounds from animal without further purification with acid chloride in Solvent to give Absolute iminio Salts and reaction without further purification in an organic Solvent (CNaphthol compounds on indole, pyrrole and / or unsubstituted or substituted,Isolation and purification of the resulting compounds by Conventional Methods and eventually reaction of Naphthol and / or indole compounds resulting in solution with organic compounds HalogEnados, in the presence of a base and eventually Filtration and purification for isolation of compounds of Naphthol and / or indole derived by Conventional Methods.
机译:在碱的存在下,在溶液中将不含质子酸P的芳香族化合物aldeh eddricos和 /或aldeh eddricos杂芳族化合物和 /或aldeh eddricos脂族化合物与仲胺反应制得的物质库在动物体内,这些化合物的反应无需进一步用酰氯在溶剂中的纯化即可得到绝对亚氨基盐,并且无需在有机溶剂中进一步纯化即可反应(吲哚,吡咯和/或未取代或取代的CNaphol化合物,分离和纯化)通过常规方法得到的化合物,并最终使萘酚和/或吲哚化合物在碱存在下与有机化合物HalogEnados溶液反应,最终进行过滤和纯化,以分离常规方法衍生的萘酚和/或吲哚化合物方法。

著录项

  • 公开/公告号CO5251473A1

    专利类型

  • 公开/公告日2003-02-28

    原文格式PDF

  • 申请/专利权人 GRUNENTHAL GMBH;

    申请/专利号CO20000097384

  • 发明设计人 GERLACH MATTHIAS;CORINNA MAUL;

    申请日2000-12-22

  • 分类号A61K31/395;

  • 国家 CO

  • 入库时间 2022-08-22 00:03:37

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