Filament - recruitment of fluorescent proteins for the analysis and identification of protein - protein - interactions: fit (filament - based interaction trap) analysis

摘要

The subject matter of the invention are bait - fusion proteins / complexes with unit -, for example, filament - in the form of the properties and prey - proteins, which is a fluorescence technical detection of recruitment in bait - structures permit. The combined use of these peptides permits the "optical" analysis of already known protein - protein - interaction, including the identification of modulators of this interaction, for example, low molecular weight not - of proteinogenous substances, but also the identification of new interaction partners of a polypeptide library prey - -.