Production of citalopram racic diol and / or citalopram s or R diodes, and the process of manufacturing citalopram racic, citalopram R and / or citalopram s with these diodes

摘要

Preparation Process of Free Base Racemic diol and / or acid Addition Salt and / or Free Base diol R S and / or acid Addition Salt, Realizing the separation of a racemic mixture of Free Base initial diol R and S and / or acid Addition Salt, with more than 50% of one of the enantiomer S in a fraction enriched with the diol diol S R and / or Free Base or acid Addition Salt.Where R: S ratio of diol diol is equal to 1: 1 or more close to 1: 1 in the initial mixture of diol R and S.