TOXICITY EVALUATION METHOD OF ENVIRONMENTAL CHEMICAL SUBSTANCE USING NEMATODE AND bis-1 NEW VARIANT NX3 USED FOR TOXICITY EVALUATION METHOD

摘要

PPROBLEM TO BE SOLVED: To provide a method for evaluating toxicity to a biological function, especially toxicity to reproduction, of a chemical substance (environmental chemical substance) having an endocrine disrupting function, accurately in a short period of time by a simple operation. PSOLUTION: This toxicity evaluation method of the environmental chemical substance is characterized by evaluating the toxicity to the biological function of the environmental chemical substance by breeding a nematode (C. elegance) and its new highly-sensitive bis-1 variant NX3 and also each variant of dpy-2, dpy-7 and dpy-10 in a culture medium including the environmental chemical substance, and by counting the number of newborns and observing the growth state and the action. PCOPYRIGHT: (C)2005,JPO&NCIPI