c-Jun phosphorylation inhibitor

摘要

c-Jun Finding BMAL1, BPL1, KIAA1491complete (SEQ ID NO: 1), or KIAA0596CT (SEQ ID NO: 2) having a function of interacting with N-terminal kinase 3, and using these and peptides derived therefrom, c-Jun Inhibition of phosphorylation, inhibition of c-Jun functions (such as transcription activation ability), suppression of apoptosis (such as suppression of apoptosis of nerve cells, etc.) and prevention of neurodegenerative diseases (such as polyglutamine disease and Alzheimer's disease) And / or pharmaceutical and pharmaceutical compositions and methods for use in therapy are provided.