HIBISCUS SABDARIFFA EXTRACT WHICH HAS INHIBITION EFFECT ON THE ACCUMULATION OF FATTY ACIDS AND THE DIFFERENTIATION OF ADIPOCYTES

摘要

PURPOSE: Provided is the Hibiscus sabdariffa extract which inhibits the accumulation of fatty acids and the differentiation of adipocytes by suppressing the expression of adipogenic transcription factors. CONSTITUTION: The extract of Hibiscus sabdariffa is characterized by suppressing the expression of CCAAT element binding protein(C/EBP)α and peroxisome proliferator-activated receptor(PPAR)γ. Therefore, the extract inhibits the accumulation of fatty acids and the differentiation of adipocytes by suppressing the expression of adipogenic transcription factors containing C/EBPα and PPARγ.