METHOD FOR TREATMENT OF HYPERHOMOCYSTENEMIA IN PATIENTS WITH CHRONIC RENAL INSUFFICIENCY AND TREATED BY HEME-DIALYSIS OR HEME-FILTRATION

摘要

FIELD: medicine.;SUBSTANCE: before onset of treatment or in the process of treatment patient is administrated 2,3-dimercaptopropane sodium sulfonate in the dose 50-500 mg by subcutaneous or intramuscular route depending on the patient mass and the expression degree of hyperhomocysteinemia. Method provides normalization of blood level homocysteine due to its elimination from body as reduced homocysteine after its complete release from blood protein-bound form and with retention of these proteins in circulation. Invention can be used in treatment of patients with renal insufficiency with the enhanced blood content of homocysteine who have increased concentration of low- and mean-molecular metabolites due to disturbance in urine formation and when carrying out heme-dialysis or heme-filtration is required.;EFFECT: improved treatment method.;5 ex