prophylactic or therapeutic treatment method of chronic kidney disease in an individual, prophylactic or therapeutic treatment method of renal insufficiency in an individual, prophylactic or therapeutic treatment method of renal fibrosis in an individual, method to reduce levels, inhibit or reduce the production of profibrotic mediators in an individual at risk of developing or who have chronic kidney disease, renal sufficiency and / or renal fibrosis established, a method for reducing collagen formation or enhancing collagen degradation in an individual's kidneys, peptide vasoactive bowel (piv) or one or more functional fragments of piv, composition for the prophylactic or therapeutic treatment of chronic kidney disease, composition for the prophylactic or therapeutic treatment of renal failure and composition for the prophylactic or therapeutic treatment of renal fibrosis

摘要

The invention relates to compositions comprising vasoactive intestinal peptide (VIP) or fragments thereof, and the use of such compositions in the treatment of kidney disease, in particular kidney fibrosis, and other associated conditions.