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circular dna molecule with a dependent replikationsursprung, its manufacturing method and its use in gene therapy
circular dna molecule with a dependent replikationsursprung, its manufacturing method and its use in gene therapy
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机译:具有依赖性复制的环状dna分子,其制备方法及其在基因治疗中的应用
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摘要
A novel circular DNA molecule (I), useful in gene therapy, comprises = 1 sequence of interest, the replication of which is controlled by an origin of replication (ORI) from a plasmid or bacteriophage, which is only active in a host cell in the presence of one or more specific proteins foreign to that cell.
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