ANIMAL FOR EVALUATION OF DRUG EFFICACY, METHOD FOR DEVELOPING ASTHMA IN ANIMAL FOR EVALUATION OF DRUG EFFICACY AND DRUG EFFICACY EVALUATION METHOD USING SAID ANIMAL

摘要

PROBLEM TO BE SOLVED: To provide an animal for the evaluation of drug efficacy attacked only by asthma and free from inflammation e.g. in the nasal cavity and the throat, a method for developing only asthma on the animal for the drug efficacy evaluation, and a method for the evaluation of selective drug efficacy to asthma by administering a drug to the animal for drug efficacy evaluation.;SOLUTION: The invention provides an animal for the evaluation of drug efficacy and developing asthma by directly applying a sensitizing substance to the lower respiratory tract of an animal except for human and directly applying a causal substance to the lower respiratory tract, a method for developing asthma on a drug efficacy evaluation animal by directly applying a sensitizing substance to the lower respiratory tract of an animal except for human and directly applying a causal substance to the lower respiratory tract, and a drug efficacy evaluation method to administer a drug to the drug efficacy evaluation animal and evaluating the action and effect of the drug.;COPYRIGHT: (C)2006,JPO&NCIPI