首页>
外国专利>
Methods and compositions for control of bone formation via modulation of sympathetic tone
Methods and compositions for control of bone formation via modulation of sympathetic tone
展开▼
机译:通过调节交感神经来控制骨形成的方法和组合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to methods for treatment, diagnosis and prevention of bone disease and comprises methods including measurement and modulation of sympathetic tone and leptin activity. Alteration of sympathetic tone in bone disease can be accomplished by decreasing or increasing leptin synthesis, leptin receptor synthesis, leptin binding to the leptin receptor, and leptin receptor activity. Alteration of sympathetic tone in bone disease can also be accomplished in the foregoing manner, in combination with traditional sympathetic nervous system agonists and/or antagonists, such as, but not limited to, a dopamine β hydroxylase antagonist or a β adrenergic antagonist for treatment or prevention of osteoporosis.
展开▼